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Here’s a breakdown of the key uses and contexts:
Some drugs once considered purely recreational or illegal are now being investigated for psychiatric treatment:
Substance | Therapeutic Use in Mental Health | Status |
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Psilocybin (magic mushrooms) | Depression, anxiety, PTSD, addiction | Clinical trials; FDA “Breakthrough Therapy” designation |
MDMA (Ecstasy) | PTSD (especially treatment-resistant) | Advanced clinical trials (Phase 3); under FDA review |
Ketamine (and esketamine) | Treatment-resistant depression, suicidal ideation | FDA-approved for depression (esketamine via nasal spray) |
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Note: These are used in clinical or research settings, not as “recreational” drugs.
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