Apaan Powder
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Buy APAAN powder online. APAAN (alpha-phenylacetoacetonitrile), also known as 2-Phenylacetoacetonitrile, is an analytical reference standard structurally categorized as an amphetamine precursor. APAAN is utilized to generate phenylacetone, which is then modified via the Leuckart reaction to synthesize amphetamine.
Chemical Information:
- Chemical Formula: C₁₀H₉NO
- Molar Mass: 159.187 g/mol
- CAS Number: 4468-48-8
APAAN: A Key Precursor for Illicit Amphetamine Production
Alpha-phenylacetoacetonitrile (APAAN) has become a significant precursor for illicit amphetamine synthesis, with its importance steadily increasing. The conversion of APAAN to benzylmethylketone (BMK) is straightforward, using a simple method that achieves high yields. This conversion primarily occurs in laboratories located in The Netherlands and Poland.
Despite its widespread use for illicit BMK production, there is limited forensic knowledge regarding APAAN, including its purity, conversion processes, yields, and characteristic BMK impurities.
Forensic Study of APAAN
Our study systematically investigates the chemistry of APAAN as an amphetamine precursor. APAAN samples from various sources were characterized using several analytical techniques, such as GC/MS, LC/MS, and 1H-NMR, to profile the substance and its impurities. Model syntheses were conducted to establish a valid database for yield calculation, investigating the most common conversion methods. The BMK produced was analyzed by GC/MS to identify characteristic impurities.
Findings:
- Purity: APAAN samples showed a purity range from 70-98%.
- Hydrolysis Yields: APAAN hydrolysis using three different inorganic acids (sulfuric acid, hydrochloric acid, and phosphoric acid) yielded 50-75%.
- BMK Impurities: Characteristic BMK impurities were identified during the conversion process.
Conclusion:
Our investigation characterized APAAN impurities and determined BMK yields from various synthesis pathways. The BMK obtained from APAAN hydrolysis was analyzed using GC/MS.
Ordering Information:
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Summary:
APAAN (alpha-phenylacetoacetonitrile) is an important precursor for the synthesis of phenylacetone, methamphetamine, and amphetamine. Its conversion to BMK is primarily conducted in The Netherlands and Poland using high-yield methods. Forensic studies have detailed APAAN’s purity, conversion processes, and characteristic impurities, providing a comprehensive understanding of this critical substance.
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